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Medical Questions > Anti-Depressants and Hypertension

Does anyone have any further information on the relationship of anti-depressants and hypertension?
April 14, 2008 | Unregistered CommenterRob Brentnall
Rob:
There is not much known about depression and the occurrence of hypertension –see the link <http://www.ncbi.nlm.nih.gov/pubmed/15962086>. Can you be a little more specific? A lot depends on what sort of antidepressant you are talking about. I doubt if there are antidepressants used today that cause hypertension as a side effect on their own. However, some may well present a risk of drug interactions leading to hypertension. For instance, monoamine oxidase inhibitors (MAOIs) given alone may rarely be linked to hypertension (the risk is less than 1%<http://www.ncbi.nlm.nih.gov/pubmed/8399806>). Severe hypertension is more likely to occur when MAOIs are combined with other drugs that have a similar mechanism of action (i.e. sympathomimetic drugs), or when amine-containing food (e.g. cheese) is eaten. <http://www.ncbi.nlm.nih.gov/pubmed/9303278> Be guided by your physician, and read the antidepressants’ package inserts. Hope this helps.
April 15, 2008 | Unregistered CommenterBob Griffith
Bob, you may want to check Effexor, Paxil, Nortriptyline, Wellbutrin SR, etc.

If you only knew.
April 18, 2008 | Unregistered CommenterRob Brentnall